“Success is dependent on effort” (Sophocles). Put forth the effort and work like your life depended on it, because it just might. Let your diligent habitual work ethic empower and motivate you to succeed, like oxygen keeping every cell in your body alive. Do not lower your standards, lest neglect, procrastination, and compromise devour dreams like a thief seeking to kill and destroy. Remember, we get what we tolerate, therefore settle for nothing less than your absolute best. Go to bed each night knowing you spent your passionate self completely, hence sleep like a baby without worry or concerns of any kind.
Downregulation decreases neurotransmitter receptors, whereas upregulation increases receptors. Sensitivity to molecules decreases with downregulation. Smoking anything containing nicotine can cause upregulation, necessitating more nicotine to obtain similar effects. Additionally, note that nicotine has an affinity for the hemoglobin molecule, which is on the red blood cell carrying oxygen to every cell in our body. Nicotine takes the place of approximately half of the oxygen molecules on hemoglobin. Remember that oxygen is life and life ends when our oxygen supply ends. In ischemia, lack of oxygen perfusing or circulating to tissue and vital organs, cells can die. If this sounds scary, it’s because it is! If you’re serious about stopping smoking—do it! Read the book, “The Little Engine That Could,” each night for 30 days. You can do anything with a changed and made up mind.