A cigarette smoker addicted to nicotine can allow the nicotine to dominate his or her thoughts, moods, actions, time, and health or the individual can take control and eradicate the poor habit, forever. Nicotine not only triggers the release of dopamine, which binds to dopanergic receptors, but can even create more dendritic dopamine receptors. Because of the increased dopamine receptors people can develop more of a tolerance that requires additional nicotine to acquire the same effects. Don’t say, “I can’t stop smoking.” Why worry about a shot not going in before you’ve even taken it? All shots not taken don’t go in. Try try again until successful. Believe that you can and do it. Once you stop, think of yourself as a nonsmoker, saying, “I don’t smoke.”
Downregulation decreases neurotransmitter receptors, whereas upregulation increases receptors. Sensitivity to molecules decreases with downregulation. Smoking anything containing nicotine can cause upregulation, necessitating more nicotine to obtain similar effects. Additionally, note that nicotine has an affinity for the hemoglobin molecule, which is on the red blood cell carrying oxygen to every cell in our body. Nicotine takes the place of approximately half of the oxygen molecules on hemoglobin. Remember that oxygen is life and life ends when our oxygen supply ends. In ischemia, lack of oxygen perfusing or circulating to tissue and vital organs, cells can die. If this sounds scary, it’s because it is! If you’re serious about stopping smoking—do it! Read the book, “The Little Engine That Could,” each night for 30 days. You can do anything with a changed and made up mind.